Genetic anomalies on the JNK pathway confer susceptibility to autism spectrum disorders, schizophrenia and intellectual disability.The mechanism whereby a Wooden Blocks gain or loss of function in JNK signaling predisposes to these prevalent dendrite disorders, with associated motor dysfunction, remains unclear.Here we find that JNK1 regulates the
It is known that design of elastic cloaks is much more challenging than that of acoustic cloaks, cloaks of electromagnetic waves or scalar problems of anti-plane shear.In this paper, we address fully the fourth-order problem and develop a model of a broadband invisibility cloak for channelling flexural waves Protection in thin plates around finite
It is widely recognized that extracellular vesicles subserve non-classical signal transmission in the central nervous system.Here we assess if the astrocyte processes, that are recognized to play crucial roles in intercellular communication at the synapses and in neuron-astrocyte networks, could convey messages through extracellular vesicles.Our Ad
Opportunistic Networks (OppNets) are characterized by intermittently connected nodes with fluctuating performance.Their dynamic topology, caused by node movement, activation, and deactivation, often relies on controlled flooding for routing, leading to significant resource consumption and network congestion.To address this challenge, we propose the